Klaus Klumpp: search on Z-Library

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1

On Protein Folding in Crowded Conditions

Gomez, David, Huber, Klaus, Klumpp, Stefan

Journal:

The Journal of Physical Chemistry Letters

Year:

2019

File:

PDF, 1.97 MB

2019

2

Capsid proteins of enveloped viruses as antiviral drug targets

Klumpp, Klaus, Crépin, Thibaut

Journal:

Current Opinion in Virology

Year:

2014

Language:

english

File:

PDF, 1.18 MB

english, 2014

3

High-resolution crystal structure of a hepatitis B virus replication inhibitor bound to the viral core protein

Klumpp, Klaus, Lam, Angela M., Lukacs, Christine, Vogel, Robert, Ren, Suping, Espiritu, Christine, Baydo, Ruth, Atkins, Kateri, Abendroth, Jan, Liao, Guochun, Efimov, Andrey, Hartman, George, Flores,

Journal:

Proceedings of the National Academy of Sciences

Year:

2015

Language:

english

File:

PDF, 1.16 MB

english, 2015

4

Impact of anthropogenic induced nitrogen input and liming on phosphorus leaching in forest soils

Holzmann, Stefan, Missong, Anna, Puhlmann, Heike, Siemens, Jan, Bol, Roland, Klumpp, Erwin, von Wilpert, Klaus

Journal:

Journal of Plant Nutrition and Soil Science

Year:

2016

Language:

english

File:

PDF, 352 KB

english, 2016

5

The application of the phosphoramidate ProTide approach confers micromolar potency against Hepatitis C virus on inactive agent 4′-azidoinosine: Kinase bypass on a dual base/sugar modified nucleoside

Christopher McGuigan, Felice Daverio, Isabel Nájera, Joseph A. Martin, Klaus Klumpp, David B. Smith

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2009

Language:

english

File:

PDF, 260 KB

english, 2009

6

Mitralklappen- und Mitralringbewegung bei Mitralstenose anhand von verschiedenen Klappenmodellen

R. Lemke, B. Braun, F. Klumpp, J. Zehner, D. Klaus

Journal:

Basic Research in Cardiology

Year:

1977

File:

PDF, 1.13 MB

1977

7

Transcriptomic analysis of the woodchuck model of chronic hepatitis B

Simon P. Fletcher, Daniel J. Chin, Yongmei Ji, A. Leonardo Iniguez, Bruce Taillon, David C. Swinney, Palanikumar Ravindran, Donavan T. Cheng, Hans Bitter, Uri Lopatin, Han Ma, Klaus Klumpp, Stephan Me

Journal:

Year:

2012

Language:

english

File:

PDF, 1.73 MB

english, 2012

8

HCV RNA Helicase Requirement for NS3 Oligomerization is Substrate-dependent: Characterization of RNA Substrates with Different Double Strand Lengths and RNA Binding-dependent Inhibition

Julie Hang, Yanli Yang, Vincent Leveque, Tony Giannetti, George Stepan, Nick Cammack, Klaus Klumpp

Journal:

Antiviral Research

Year:

2008

Language:

english

File:

PDF, 61 KB

english, 2008

9

2′-Deoxy-nucleoside Analogs can be Potent Dual Inhibitors of HCV and HIV Replication with Selectivity against Human Polymerases

Klaus Klumpp, Guoping Su, Vincent Leveque, Jerome Deval, Gabrielle Heilek, Sonal Rajyaguru, Yu Li, Julie Q. Hang, Han Ma, Nicole Inocencio, Genadiy Kalayanov, Anna Winqvist, David B. Smith, Nick Camma

Journal:

Antiviral Research

Year:

2009

Language:

english

File:

PDF, 69 KB

english, 2009

10

SAR Studies in the Sulfonyl Carboxamide Class of HBV Capsid Assembly Modulators

Kuduk, Scott D., Lam, Angela M., Espiritu, Christine, Vogel, Robert, Lau, Vincent, Klumpp, Klaus, Flores, Osvaldo A., Hartman, George D.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2019

Language:

english

File:

PDF, 350 KB

english, 2019

11

MRI of muscular fat

Fritz Schick, Jürgen Machann, Klaus Brechtel, Andrea Strempfer, Bernhard Klumpp, Daniel T. Stein, Stephan Jacob

Journal:

Magnetic Resonance in Medicine

Year:

2002

Language:

english

File:

PDF, 4.16 MB

english, 2002

12

Identification of an intrahepatic transcriptional signature associated with self-limiting infection in the woodchuck model of hepatitis B

Fletcher, Simon P., Chin, Daniel J., Cheng, Donavan T., Ravindran, Palanikumar, Bitter, Hans, Gruenbaum, Lore, Cote, Paul J., Ma, Han, Klumpp, Klaus, Menne, Stephan

Journal:

Year:

2013

Language:

english

File:

PDF, 3.39 MB

english, 2013

13

The application of phosphoramidate ProTide technology to the potent anti-HCV compound 4′-azidocytidine (R1479)

Christopher McGuigan, Mary Rose Kelleher, Plinio Perrone, Sinead Mulready, Giovanna Luoni, Felice Daverio, Sonal Rajyaguru, Sophie Le Pogam, Isabel Najera, Joseph A. Martin, Klaus Klumpp, David B. Smi

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2009

Language:

english

File:

PDF, 288 KB

english, 2009

14

Successes and challenges in the antiviral field

Shaw, Megan L, Klumpp, Klaus

Journal:

Current Opinion in Virology

Year:

2013

Language:

english

File:

PDF, 135 KB

english, 2013

15

Design, synthesis, and antiviral properties of 4′-substituted ribonucleosides as inhibitors of hepatitis C virus replication: The discovery of R1479

David B. Smith, Joseph A. Martin, Klaus Klumpp, Stewart J. Baker, Peter A. Blomgren, Rene Devos, Caroline Granycome, Julie Hang, Christopher J. Hobbs, Wen-Rong Jiang, Carl Laxton, Sophie Le Pogam, Vin

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2007

Language:

english

File:

PDF, 174 KB

english, 2007

16

Design and Characterization of R1626, A Prodrug of the HCV Replication Inhibitor R1479 (4′-Azidocytidine) With Enhanced Oral Bioavailability

Klaus Klumpp, David Smith, Michael Brandl, Tom Alfredson, Keshab Sarma, Mark Smith, Isabel Najera, Wen-Rong Jiang, Sophie Le Pogam, Vincent Leveque, Han Ma, Yaping Tu, Rebecca Chan, Chiao-Wen Chen, Xi

Journal:

Antiviral Research

Year:

2007

Language:

english

File:

PDF, 65 KB

english, 2007

17

Recent Progress in the Design of Small Molecule Inhibitors of HIV RNase H

Klumpp, Klaus, Mirzadegan, Tara

Journal:

Current Pharmaceutical Design

Year:

2006

Language:

english

File:

PDF, 286 KB

english, 2006

18

Zyklisches AMP und Reninaktivität im Nierenvenenplasma nach Amitryptilin, Theophyllin, Furosemid und beta-adrenergen Rezeptorantagonisten

J. Zehner, D. Klaus, F. Klumpp, R. Lemke

Journal:

Journal of Molecular Medicine

Year:

1976

File:

PDF, 905 KB

1976

19

Silibinin (Legalon-SIL) Inhibits HCV Replication In Vitro

Isabel Najera, Vincent Leveque, Matt McCown, Julie Q. Hang, Han Ma, Sonal Rajyaguru, Amy Fung, Yanli Yang, Yang Liu, Simran Kular, Nick Cammack, Peter Ferenci, Klaus Klumpp

Journal:

Antiviral Research

Year:

2009

Language:

english

File:

PDF, 72 KB

english, 2009

20

Characterization of the Intracellular Metabolism of β-d-2′-Deoxy-2′-Fluoro-2′-C-Methyl-Cytidine and the Inhibition of HCV Polymerase NS5B by its 5′-Triphosphate Species

Han Ma, Wen-Rong Jiang, Nicole Robledo, Vincent Leveque, Samir Ali, David Smith, Mohammad Masjedizadeh, Teresa Lara-Jaime, Nick Cammack, Klaus Klumpp, Julian Symons

Journal:

Antiviral Research

Year:

2007

Language:

english

File:

PDF, 68 KB

english, 2007

21

Orally bioavailable prodrugs of a BCS class 2 molecule, an inhibitor of HIV-1 reverse transcriptase

Todd R. Elworthy, James P. Dunn, J. Heather Hogg, Grace Lam, Y. David Saito, Tania M.P.C. Silva, Dimitrios Stefanidis, Witold Woroniecki, Eugenia Zhornisky, Amy S. Zhou, Klaus Klumpp

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 207 KB

english, 2008

22

Activity of the isolated HIV RNase H domain and specific inhibition by N-hydroxyimides

Julie Qi Hang, Surendran Rajendran, Yanli Yang, Yu Li, Philippe Wong Kai In, Hilary Overton, Kevin E.B. Parkes, Nick Cammack, Joseph A. Martin, Klaus Klumpp

Journal:

Biochemical and Biophysical Research Communications

Year:

2004

Language:

english

File:

PDF, 1.97 MB

english, 2004

23

Quantitative Analysis of Influenza Virus RNP Interaction with RNA Cap Structures and Comparison to Human Cap Binding Protein eIF4E

Hooker, Lisa, Sully, Rachel, Handa, Balraj, Ono, Naomi, Koyano, Hiroshi, Klumpp, Klaus

Journal:

Year:

2003

Language:

english

File:

PDF, 190 KB

english, 2003

24

2′- and 4′-Modified Ribonucleoside Analogs Can Inhibit All Four Serotypes of Dengue Virus in Human Primary Dendritic Cells as Competitive Inhibitors and Non-obligatory Chain Terminators

Hassan Javanbakht, Vincent Leveque, Zhinan Jin, Jerome Deval, Andreas Jekle, Gabrielle Heilek, Han Ma, Klaus Klumpp

Journal:

Antiviral Research

Year:

2011

Language:

english

File:

PDF, 69 KB

english, 2011

25

The hepatitis C virus NS5A inhibitor (BMS-790052) alters the subcellular localization of the NS5A non-structural viral protein

Choongho Lee, Han Ma, Julie Qi Hang, Vincent Leveque, Ella H. Sklan, Menashe Elazar, Klaus Klumpp, Jeffrey S. Glenn

Journal:

Year:

2011

Language:

english

File:

PDF, 1.29 MB

english, 2011

26

Radioimmunologische Bestimmung von Aldosteron im Plasma

Klumpp, F., Rössler, R., Klaus, D.

Journal:

Clinical Chemistry and Laboratory Medicine

Year:

1974

Language:

german

File:

PDF, 1.20 MB

german, 1974

27

Optimization of Small Molecule Drugs Binding to Highly Polar Target Sites: Lessons from the Discovery and Development of Neuraminidase Inhibitors

Klumpp, Klaus, Graves, Bradford

Journal:

Current Topics in Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 414 KB

english, 2006

28

Leaching of natural colloids from forest topsoils and their relevance for phosphorus mobility

Missong, Anna, Holzmann, Stefan, Bol, Roland, Nischwitz, Volker, Puhlmann, Heike, v. Wilpert, Klaus, Siemens, Jan, Klumpp, Erwin

Journal:

Science of The Total Environment

Year:

2018

Language:

english

File:

PDF, 1.62 MB

english, 2018

29

Reconstitution and Functional Analysis of a Full-Length Hepatitis C Virus NS5B Polymerase on a Supported Lipid Bilayer

Cho, Nam-Joon, Pham, Edward A., Hagey, Rachel J., Lévêque, Vincent J., Ma, Han, Klumpp, Klaus, Glenn, Jeffrey S.

Journal:

ACS Central Science

Year:

2016

Language:

english

File:

PDF, 2.92 MB

english, 2016

30

HBV Capsid Assembly Modulators, but not Nucleoside Analogs, Inhibit the Production of Extracellular Pregenomic RNA and Spliced RNA Variants

Lam, Angela M, Ren, Suping, Espiritu, Christine, Kelly, Mollie, Lau, Vincent, Zheng, Lingjie, Hartman, George D, Flores, Osvaldo A, Klumpp, Klaus

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2017

Language:

english

File:

PDF, 1.24 MB

english, 2017

31

Immune cell responses are not required to induce substantial hepatitis B virus antigen decline during pegylated interferon-alpha administration

Allweiss, Lena, Volz, Tassilo, Lütgehetmann, Marc, Giersch, Katja, Bornscheuer, Till, Lohse, Ansgar W., Petersen, Joerg, Ma, Han, Klumpp, Klaus, Fletcher, Simon P., Dandri, Maura

Journal:

Journal of Hepatology

Year:

2014

Language:

english

File:

PDF, 959 KB

english, 2014

32

Spironolacton und Thiabutazid bei der Behandlung der essentiellen Hypertonie *

Klumpp, F., Braun, B., Klaus, D., Lemke, R., Zehner, J., Zöfel, P.

Journal:

DMW - Deutsche Medizinische Wochenschrift

Year:

1975

Language:

german

File:

PDF, 175 KB

german, 1975

33

Donor Lymphocyte Infusion in Hematologic Malignancies—Good to be Fresh?

Hossain, Nasheed Mohammad, Klumpp, Thomas, Ulicny, John, Garner, Michael, Kropf, Patricia Lamont, Mangan, Kenneth F., Barta, Stefan Klaus, Fung, Henry C., Martin, Mary Ellen

Journal:

Clinical Lymphoma Myeloma and Leukemia

Year:

2016

Language:

english

File:

PDF, 347 KB

english, 2016

34

Mößbauereffekt in FeCl2, FeSO4und FeSO4· 7 H2O

Walter Klumpp, Klaus -Werner Hoffmann

Journal:

Zeitschrift für Physik A Hadrons and Nuclei

Year:

1969

File:

PDF, 286 KB

1969

35

Erratum

Allweiss, Lena, Volz, Tassilo, Lütgehetmann, Marc, Giersch, Katja, Bornscheuer, Till, Lohse, Ansgar W., Petersen, Joerg, Ma, Han, Klumpp, Klaus, Fletcher, Simon P., Dandri, Maura

Journal:

Year:

1989

File:

PDF, 38 KB

1989

36

Efficacy of NVR 3-778, Alone and in Combination With Pegylated Interferon, vs Entecavir in uPA/SCID Mice With Humanized Livers and HBV Infection

Klumpp, Klaus, Shimada, Takashi, Allweiss, Lena, Volz, Tassilo, Lütgehetmann, Marc, Hartman, G., Flores, Osvaldo A., Lam, Angela M., Dandri, Maura

Journal:

Gastroenterology

Year:

2017

Language:

english

File:

PDF, 2.26 MB

english, 2017

37

Das Verhalten des Plasmaaldosterons und der Plasmareninaktivität bei primärer und renaler Hypertonie unter Stimulations- und Suppressionsbedingungen

F. Klumpp, D. Klaus, R. Lemke, J. Zehner, P. Zöfel

Journal:

Journal of Molecular Medicine

Year:

1975

File:

PDF, 1.05 MB

1975

38

A Novel Immuno-Competitive Capture Mass Spectrometry Strategy for Protein–Protein Interaction Profiling Reveals That LATS Kinases Regulate HCV Replication Through NS5A Phosphorylation*

Meistermann, Hélène, Gao, Junjun, Golling, Sabrina, Lamerz, Jens, Le Pogam, Sophie, Tzouros, Manuel, Sankabathula, Sailaja, Gruenbaum, Lore, Nájera, Isabel, Langen, Hanno, Klumpp, Klaus, Augustin, Ang

Journal:

Molecular & Cellular Proteomics

Year:

2014

Language:

english

File:

PDF, 1.01 MB

english, 2014

39

Die Behandlung der essentiellen Hypertonie mit Propranolol *

Klumpp, F., Braun, B., Klaus, D., Lemke, R., Zehner, J.

Journal:

DMW - Deutsche Medizinische Wochenschrift

Year:

1976

File:

PDF, 1.64 MB

1976

40

The radioprotector ortho-phospho- L -tyrosine (pTyr) attenuates the side effects of fractionated irradiation in retinoblastoma mouse models but also decreases the local tumour control

Tschulakow, Alexander V., Dittmann, Klaus, Huber, Stephan M., Klumpp, Dominik, Stegen, Benjamin, Schraermeyer, Ulrich, Rodemann, H. Peter, Julien-Schraermeyer, Sylvie

Journal:

Radiotherapy and Oncology

Year:

2017

Language:

english

File:

PDF, 718 KB

english, 2017

41

Robust antiviral activity of R1626, a novel nucleoside analog: A randomized, placebo-controlled study in patients with chronic hepatitis C

Stuart K. Roberts, Graham Cooksley, Gregory J. Dore, Richard Robson, David Shaw, Heather Berns, George Hill, Klaus Klumpp, Isabel Najera, Carla Washington

Journal:

Year:

2008

Language:

english

File:

PDF, 511 KB

english, 2008

42

Intraindividual comparison of myocardial delayed enhancement MR imaging using gadobenate dimeglumine at 1.5

Bernhard D. Klumpp, Joern Sandstede, Klaus P. Lodemann, Achim Seeger, Tobias Hoevelborn, Michael Fenchel, Ulrich Kramer, Claus D. Claussen, Stephan Miller

Journal:

European Radiology

Year:

2009

Language:

english

File:

PDF, 266 KB

english, 2009

43

Applications of Parallel Synthesis to Lead Optimization

Altorfer, Michael, Ermert, Philipp, Fässler, Jürg, Farooq, Saleem, Hillesheim, Elke, Jeanguenat, André, Klumpp, Klaus, Maienfisch, Peter, Martin, Joseph A., Merrett, John H., Parkes, Kevin E.B., Obrec

Journal:

CHIMIA International Journal for Chemistry

Year:

2003

Language:

english

File:

PDF, 137 KB

english, 2003

44

Applications of Parallel Synthesis to Lead Optimization

Michael Altorfer, Philipp Ermert, Juerg Faessler, Saleem Farooq, Elke Hillesheim, Andre Jeanguenat, Klaus Klumpp, Peter Maienfisch, Joseph A. Martin, John H. Merrett, et al. et al.

Journal:

Year:

2004

File:

PDF, 50 KB

2004

45

Adsorption of 2,4-Dichlorophenol on Montmorillonite and Silica: Influence of Nonionic Surfactants

Wolfgang Klaus Backhaus, Erwin Klumpp, Hans-Dieter Narres, Milan Johann Schwuger

Journal:

Journal of Colloid and Interface Science

Year:

2001

Language:

english

File:

PDF, 89 KB

english, 2001

46

Oseltamivir in seasonal, pandemic, and avian influenza: a comprehensive review of 10-years clinical experience

James R. Smith, Craig R. Rayner, Barbara Donner, Martina Wollenhaupt, Klaus Klumpp, Regina Dutkowski

Journal:

Advances in Therapy

Year:

2011

Language:

english

File:

PDF, 1019 KB

english, 2011

47

Combinations of oseltamivir and peramivir for the treatment of influenza A (H1N1) virus infections in cell culture and in mice

Donald F. Smee, Brett L. Hurst, Min-Hui Wong, E. Bart Tarbet, Y.S. Babu, Klaus Klumpp, John D. Morrey

Journal:

Antiviral Research

Year:

2010

Language:

english

File:

PDF, 709 KB

english, 2010

48

Long-Term Follow-up and Experience with Donor Lymphocyte Infusion (DLI); Is It Time for a Paradigm Shift?

Hossain, Nasheed Mohammad, Klumpp, Thomas, Ulicny, John, Garner, Michael, Kropf, Patricia Lamont, Mangan, Kenneth F., Barta, Stefan Klaus, Fung, Henry C., Martin, Mary Ellen

Journal:

Biology of Blood and Marrow Transplantation

Year:

2015

Language:

english

File:

PDF, 405 KB

english, 2015

49

Chemical phosphorylation of histidine-containing peptides based on the sequence of histone H4 and their dephosphorylation by protein histidine phosphatase

Paul V. Attwood, Katrin Ludwig, Klaus Bergander, Paul G. Besant, Abdussalam Adina-Zada, Josef Krieglstein, Susanne Klumpp

Journal:

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics

Year:

2010

Language:

english

File:

PDF, 745 KB

english, 2010

50

First Example of Phosphoramidate Approach Applied to a 4‘-Substituted Purine Nucleoside (4‘-Azidoadenosine): Conversion of an Inactive Nucleoside to a Submicromolar Compound versus Hepatitis C Virus

Perrone, Plinio, Daverio, Felice, Valente, Rocco, Rajyaguru, Sonal, Martin, Joseph A., Lévêque, Vincent, Pogam, Sophie Le, Najera, Isabel, Klumpp, Klaus, Smith, David B., McGuigan, Christopher

Journal:

Journal of Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 130 KB

english, 2007

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